_Federico I GONZAGA __________________+
                                                                             | (1441 - 1484)                        
                                         _Francesco II GONZAGA ______________|
                                        | (1466 - 1519)                      |
                                        |                                    |_Margaretha of WITTELSBACH ___________+
                                        |                                      (1442 - 1479)                        
 _Frederico II GONZAGA _________________|
| (1500 - 1540)                         |
|                                       |                                     _Ercole I of ESTE ____________________+
|                                       |                                    | (1431 - 1504)                        
|                                       |_Isabella of ESTE __________________|
|                                         (1474 - 1538)                      |
|                                                                            |_Eleonora of TRASTÁMARA _____________+
|                                                                              (1450 - 1493)                        
|
|--Isabella of GONZAGA 
|  
|                                                                             _Boniface III PALAIOLOGOS-MONTFERRAT _+
|                                                                            | (1426 - 1494)                        
|                                        _William IX PALAIOLOGOS-MONTFERRAT _|
|                                       | (1486 - 1518)                      |
|                                       |                                    |_Marija of BRANKOVIĆ ________________+
|                                       |                                      (1466 - 1495)                        
|_Margherita of PALAIOLOGOS-MONTFERRAT _|
  (1510 - 1566)                         |
                                        |                                     _Rene VALOIS _________________________+
                                        |                                    | (1454 - 1492) m 1488                 
                                        |_Anne of VALOIS ____________________|
                                          (1492 - 1562)                      |
                                                                             |_Margaret of LORRAINE ________________+
                                                                               (1463 - 1521) m 1488