Founder of the Antipatrid Dynasty

A son of Antipater and a contemporary of Alexander the Great, Cassander was one of the Diadochi who warred over Alexander's empire following the latter's death in 323 BC. Cassander later seized power by having Alexander's son and heir Alexander IV murdered. While governing Macedonia from 317 BC until 297 BC, Cassander focused on strengthening the northern borders and economic development, while founding or restoring several cities (including Thessalonica, Cassandreia, and Thebes); however, his ruthlessness in dealing with political enemies complicates assessments of his rule.

In his youth, Cassander was taught by the philosopher Aristotle at the Lyceum in Macedonia. He was educated alongside Alexander the Great in a group that included Hephaestion, Ptolemy and Lysimachus. His family were distant collateral relatives to the Argead dynasty.

Cassander is first recorded as arriving at Alexander the Great's court in Babylon in 323 BC, where he had been sent by his father, Antipater, most likely to help uphold Antipater's regency in Macedon, although a later contemporary who was hostile to the Antipatrids suggested that Cassander had journeyed to the court to poison the King. Cassander left Alexander's court either shortly before or after the king's death in June of 323 BC, playing no part in the immediate power struggles over the empire. Cassander returned to Macedonia and assisted his father's governance, he was later assigned by Antipater to Antigonus as his chiliarch from 321 to 320, probably to monitor the latter's activities.

As Antipater grew close to death in 319 BC, he transferred the regency of Macedon not to Cassander, but to Polyperchon, possibly so as not to alarm the other Diadochi through an apparent move towards dynastic ambition, but perhaps also because of Cassander's own ambitions. Cassander rejected his father's decision, and immediately went to seek the support of Antigonus, Ptolemy and Lysimachus as his allies. Waging war on Polyperchon, Cassander destroyed his fleet, put Athens under the control of Demetrius of Phaleron, and declared himself Regent in 317 BC. After Olympias' successful move against Philip III later in the year, Cassander besieged her in Pydna. When the city fell in the spring of 316, Olympias was killed, and Cassander had Alexander IV and Roxana confined at Amphipolis.

That year, Cassander associated himself with the Argead dynasty by marrying Alexander's half-sister, Thessalonike, and overseeing the burial of Phillip III and Eurydice in the royal cemetery at Aegae; he further cemented his authority by founding Thessalonica, Cassandreia, and rebuilding Thebes. From 314 to 310, Cassander campaigned to the west and north, for a time extending Macedonian power as far as Apollonia and Epidamus, but was driven out by local rulers like Glaucius; his rule in Macedonia remained firm as he resettled defeated enemies in the tradition of Phillip II and fostered trade in the regions around his new cities. Cassander had Alexander IV and Roxana secretly poisoned in either 310 BC or the following year.

Cassander's dynasty did not live much beyond his death, with his son Philip dying of natural causes, and his other sons Alexander and Antipater becoming involved in a destructive dynastic struggle along with their mother. When Alexander was ousted as joint king by his brother, Demetrius I took up Alexander's appeal for aid and ousted Antipater, killed Alexander V and established the Antigonid dynasty. The remaining Antipatrids, such as Antipater II Etesias, were unable to re-establish the Antipatrids on the throne.